Top 10 Comic Book Releases This Week: Grab these now! 10/22/2025

Introduction

This week has brought an exciting array of new comic book releases from Marvel, D.C., Image, and other publishers that have captured the imagination of readers worldwide. This blog post counts down our top ten picks for the week, each showcasing remarkable storytelling and striking artwork. Make sure to check back every week for our Top 10 Hot New Comic Books List. We want to thank MyComicShop.com for partnering with us on this venture.

Please note that this site includes affiliate links, meaning we may receive a small commission if you purchase something through our links at no extra cost to you. Using these links helps support the upkeep of this website.

10. Radioactive Spider-Man #1 – Peter Parker’s Most Dangerous Gamble Yet

In a world ravaged by the X-Virus and near-total mutant domination, Peter Parker makes a desperate choice—he doses himself with lethal radiation to keep the infection at bay. What he gains may save lives. What he loses could destroy who he is.

About the Comic

Set ten years in the future under the event Age of Revelation, New York has been devastated by the X-Virus and mutant-dominated forces. In Radioactive Spider-Man #1, the formerly friendly neighborhood hero plunges into a brutal new reality. With his body a ticking time-bomb and the threat of mutation ever-looming, Peter swings back into the streets—if he survives long enough.

A Deep Dive

• Key issue alert: Launches a bold new Spider-Man status quo under Age of Revelation—makes this issue an important cornerstone for the run.

• Character spotlight: Peter Parker goes beyond heroism. His self-sacrifice to contain the X-Virus places him in unprecedented territory—both physically and morally.

• World-building: The backdrop is catastrophic: an Earth reshaped by mutant dominion, disease, and survival. This issue expands Spider-Man’s sphere far beyond New York’s rooftops.

• Visual tone & style: The art and cover hint at mutation, overload, and desperation. Expect chaotic action and the glazed glare of a hero pushed beyond his limits.

• Creators: Written by Joe Kelly; art by Kev Walker; colors by Chris Sotomayor; lettering by VC Joe Caramagna; cover art by Giuseppe Camuncoli (with variant covers by other artists).

Target Audience

• Fans of Spider-Man who want to see Peter Parker challenged like never before—physically, morally, and existentially.

• Readers drawn to high-stakes event tie-ins and alternate futures—especially where familiar heroes land in unfamiliar, unforgiving world.

• Collectors: A #1 issue kicking off a major tie-in run for a top-tier character in a major event. Strong variant possibilities, high narrative weight—worth grabbing early.

Summary

Radioactive Spider-Man #1 pushes Peter Parker into survival mode on a global scale—dealing with mutation, decay and the legacy of the X-Virus under a new, harsher world. With a strong creative team, major status quo shift, and visual stakes that scream change, this issue is essential for both readers and collectors alike.

👉 Add Radioactive Spider-Man #1 to your collection today: Affiliate Link

9. Fantastic Four #4 – When Time Fractures, the First Family Faces Its Greatest Puzzle

The bow ties are off and the watch is ticking: the First Family unravels a mystery that rings through multiple eras, forcing them to trust each other as never before. In this issue, the consequences of time travel begin to crack the foundation of everything they know.

About the Comic

In Fantastic Four #4, Reed Richards, Sue Storm, Johnny Storm and Ben Grimm continue their journey through time and space. While unraveling a high-stakes mystery tied to their recent era-hopping adventure, they encounter strange new allies—and equally strange distortions of reality. The team must decide whether the threat is what they fight or when they fight.

A Deep Dive

• Key issue alert: This issue builds off the momentum of the 2025 relaunch—issue #4 is early enough to carry strong narrative-weight and set new status quo.

• Character spotlight: The Fantastic Four are stretched (literally and figuratively) across time; their cohesion is tested as they face era-shifts and unknown forces working in the cracks.

• Scale and consequence: Time travel escapades point to deeper fallout—what seemed like adventure begins showing as danger, and the “science friend-family” dynamic is under indirect threat.

• Visual style & tone: With art by Humberto Ramos & Victor Olazaba and colors by Edgar Delgado, the visuals lean heavily on expressive faces, dramatic shadows, and surreal time-flux effects.

• Creators: Written by Ryan North; art by Humberto Ramos (pencils) & Victor Olazaba (inks); colors by Edgar Delgado; story and visuals mark the new ongoing era.

Target Audience

• Fans of the Fantastic Four who want a fresh start: this is the early part of their 2025 volume, when new directions are forming.

• Readers who enjoy high-concept science fiction blended with family drama, heroism, and legacy.

• Collectors: Issue #4 of a relaunch is early in the run; with a strong creative team and a change in status quo, this is a smart pick to secure early.

Summary

Fantastic Four #4 isn’t just another step—it’s a leap deeper into time, into mystery, and into what it means to be a family of heroes. With adventurous stakes, inventive art, and the promise of rippling consequences, this issue is both a must-read for fans and a compelling addition for collectors.

👉 Add Fantastic Four #4 to your collection today: Affiliate Link

8. Teenage Mutant Ninja Turtles #12 – The Shadows Deepen in New York’s Underbelly

The Turtles face a threat that forces them out of the sewers and into the glimmering yet dangerous streets of Manhattan. In this issue, hidden allies surface and the fight for New York’s soul begins in earnest.

About the Comic

In Teenage Mutant Ninja Turtles #12, the team is drawn into a web of power and betrayal when New York’s underworld sends a message—and it lands directly in their territory. As actions escalate, the Turtles must decide where their loyalties lie and how far they’ll go to protect the city they call home.

A Deep Dive

• Key issue alert: This issue is a critical point in the ongoing TMNT run—collectors will want to pick it up early for the shifting dynamics it introduces.

• Character spotlight: The Turtles are pushed into territories outside their comfort zone—both physically and morally. Team cohesion is tested and new players emerge.

• Underground stakes: The sewers were familiar territory; now the high-rises and glitzy corridors of Manhattan hold the danger. Expect new alliances and hidden agendas.

• Visual tone: The art swings between gritty shadows and urban lights—balancing what’s familiar about the Turtles with what’s new and unpredictable.

• Creators: Written by Jason Aaron; art by Juan Ferreyra; cover art (Cover A) also by Juan Ferreyra.

Target Audience

• Fans of the TMNT who want the series to expand—moving beyond the sewers and showing the full breadth of New York’s danger zones.

• Readers who enjoy stories of legacy teams facing new challenges, new environments, and the consequences of stepping outside comfort.

• Collectors: An issue deep in the current run where status quo is shifting, creative team is in demand, and variant covers are available. A wise pick for building value early.

Summary

Teenage Mutant Ninja Turtles #12 reflects both the familiar and the new: the Turtles’ core remains, but the environment and stakes evolve. With dynamic art, shifting alliances, and urban danger that hits close to home, this issue is essential reading—and a smart addition to any collection.

👉 Add Teenage Mutant Ninja Turtles #12 to your collection today by clicking here: Affiliate Link

7. Justice League Unlimited #12 – A One-Way Mission to the Planet’s Core

When a mysterious Terrifictech signal pulls the League to Earth’s core, time-displaced heroes assemble for a high-stakes, one-way mission. Failure isn’t just defeat—it could mean the end of the world as we know it.

About the Comic

In issue #12, the threat from the tournament of the “DC K.O.” event takes center stage. Michael Holt leads an elite squad of the most powerful League members on a mission that doesn’t promise a return. As the device buried deep in Earth’s crust activates, the League must confront a corrosion of reality—and themselves.

A Deep Dive

• Key issue alert: This is a pivotal entry tied to the major DC K.O. event—important for readers and collectors following the crossover.

• Character spotlight: Michael Holt takes charge, assembling a team of displaced heroes—his leadership is tested like never before.

• Stakes at scale: The mission is one-way, the threat existential, and the environment unforgiving—Earth’s core becomes the battleground.

• World-building: The tournament backdrop collides with personal heroism as the League transitions from world-defenders to suicide squad.

• Artwork highlight: The visuals amplify the depth of the Earth, the tension of a doomed mission, and the resolve of heroes in crisis.

• Creators: Writer: Mark Waid; Artist & main Cover: Dan Mora; Colorist: Tamra Bonvillain; Letterer: Ariana Maher.

Target Audience

• Fans of the Justice League who appreciate high-stakes superhero events where survival is uncertain.

• Readers drawn to crossover arcs and dynamic shifts where heroes face existential challenges, not just physical ones.

• Collectors: A #12 issue in a major event, with a premium creative team and significant plot import—worth securing early.

Summary

Justice League Unlimited #12 pushes the League into a mission where return isn’t guaranteed and the stakes couldn’t be higher. With cosmic tension, heavy emotional and physical cost, and a major event tie-in, this is an installment you’ll want to read and own.

👉 Add Justice League Unlimited #12 to your collection today by clicking here: Affiliate Link

6. Ultimate Spider-Man: Incursion #5 – The Ultimate Exit!

The clock is ticking as Miles Morales and his baby sister Billie race to escape the collapsing Ultimate Universe, but their exit might leave wounds neither dimension can heal. This issue brings the saga to its tipping point.

About the Comic

In Ultimate Spider-Man: Incursion #5, Miles confronts the formidable Maker’s Council in a final stand—knowing that saving the Ultimate Universe may mean sacrificing parts of his own future. With everything on the line, this chapter forces Miles to choose which universe he truly belongs to and what he’s willing to lose.

A Deep Dive

• Key issue alert: Serves as the climactic conclusion of the five-issue limited series—collectors should mark this as a major pivot point.

• Character spotlight: Miles Morales is front and center, navigating inter-dimensional threats, moral dilemmas, and the weight of the universe on his shoulders. Trust, family, legacy—all collide here.

• Stakes & scale: The threat isn’t just a villain—it’s the fate of entire universes. The Maker’s Council looms large, and this issue puts both Miles and his sister under extreme pressure.

• World-building: The Ultimate Universe’s seams are bursting. This issue promises fallout, closures, and a new direction for both Miles and the broader universe. It sets up what comes next.

• Creators: Written by Deniz Camp & Cody Ziglar Art by Jonas Scharf Cover art by Sara Pichelli

Target Audience

• Fans who follow Miles Morales and want to see his journey reach a decisive moment.

• Readers drawn to multiverse storytelling, sweeping stakes, and emotional stakes for teenage heroes turned global protectors.

• Collectors: A conclusion issue of a major crossover limited series with high impact and a top creative lineup—expect high value for early issues.

Summary

Ultimate Spider-Man: Incursion #5 delivers a culminative chapter in an epic saga of sacrifice, identity, and inter-universal consequences. With Miles at the center of world-shaking events and the creative team firing on all cylinders, this issue is a must-own for fans and collectors alike.

👉 Add Ultimate Spider-Man: Incursion #5 to your collection today by clicking here: Affiliate Link

5. Superman #31 – Into the Heart of Apokolips

The Man of Steel and his allies descend on Earth’s core in a desperate bid to seize the mysterious Heart of Apokolips—and the deeper truth may challenge everything Superman believes about his power, his Kryptonian roots, and his mission.

About the Comic

In Superman #31, Superman is thrust into the major event following the “DC K.O.” storyline. As the Heart of Apokolips lies deep beneath the planet’s surface, Clark Kent must venture into uncharted, dangerous territory—while questioning how his heritage, his responsibility, and the fate of Earth are tied together.

A Deep Dive

• Key issue alert: A pivotal chapter with huge event-tie-in implications, marking a high point in the current Superman run and major crossover stakes.

• Character spotlight: Superman is challenged not just by an enemy, but by the magnitude of his legacy and what it means to protect Earth when the roots of Apokolips reach up from below.

• Moral & cosmic stakes: The Heart of Apokolips and its connection to Krypton bring existential threat into Clark’s core identity—and the ramifications could be universe-spanning.

• World-building: The journey below Earth’s surface redefines Superman’s battleground: from Metropolis skies to hidden depths, and from alien threats to cosmic heritage.

• Creators: Written by Joshua Williamson; art by Eddy Barrows; cover by Dan Mora (with multiple variant covers available).

Target Audience

• Fans of Superman who want high-stakes event storytelling where the mythos expands and the hero is tested at his roots.

• Readers who enjoy crossover issues where the protagonist faces both internal and external conflicts on a massive scale.

• Collectors: As a major event entry, with variant covers and a strong creative team, this issue is a strong candidate for value and long-term interest.

Summary

Superman #31 forces Clark Kent into a mission that threatens not just his home but his understanding of what he defends. With cosmic intrigue, heritage revelations, and world-shaking stakes, this installment is essential reading—and a strong pickup for any collection.

👉 Add Superman #31 to your collection today: Affiliate Link

4. Detective Comics #1102 – The Virus Inside the Bat

When a weaponized virus infects the Dark Knight himself, Bruce Wayne faces not only external foes but a battle for his body and mind. And time is the enemy he cannot see.

About the Comic

In Detective Comics #1102, Batman discovers he’s been infected by a mysterious pathogen—one that threatens to strip him of control. With his mind and body under siege, Batman turns to an unlikely ally: the genius mind of Mr. Terrific. The question becomes: can Gotham’s protector survive when his most powerful asset—himself—is the threat?

A Deep Dive

• Key issue alert: Batman is compromised at his core—this issue marks a major turning point in the run and raises existential stakes.

• Character spotlight: Bruce Wayne must confront his own vulnerability while reaching out to Mr. Terrific for help—his independence challenged like never before.

• Moral & medical stakes: The virus isn’t just a physical threat—it pushes Batman’s discipline, methods, and trust in his allies to the brink.

• City at risk: As Batman falters, Gotham’s underworld shifts. With its guardian weakened, the city becomes a more dangerous place—and every second lost matters.

• Creators: Written by Tom Taylor; art by Mikel Janín; colors by Lee Loughridge; lettering by Wes Abbott.

Target Audience

• Fans of Batman who appreciate stories that expose the hero’s human limits—and show what happens when even the Dark Knight is vulnerable.

• Readers drawn to high-stakes thrillers with medical, psychological, and detective elements merging in a superhero setting.

• Collectors: A major narrative inflection point in a flagship Batman title, with a prominent creative team—this issue holds strong potential for future significance.

Summary

Detective Comics #1102 throws Bruce Wayne into his greatest internal fight yet—where the enemy is inside, the timeline is shrinking, and Gotham waits. With intense art, deep vulnerability, and a plot that could redefine what it means to protect the city, this issue is essential for fans and a smart pick for collectors.

👉 Add Detective Comics #1102 to your collection today: Affiliate Link

3. The Ultimates #17 – Doom’s Ultimate Fantastic Four Emerges

As the Immortus Engine reaches full capacity, the dream of an “Ultimate Fantastic Four” stands on the brink of reality—and the consequences could reshape the Universe. This issue brings the next phase of the series into high gear.

About the Comic

In The Ultimates #17, the team moves deeper into conflict with the Maker’s Council while the Immortus Engine unleashes new possibilities. When Reed Richards takes the alias of Doom and timelines fracture, the Ultimates must fight history itself—not just enemies.

A Deep Dive

• Key issue alert: This issue introduces the major threat of the “Ultimate Fantastic Four” concept—collectors will want this as a milestone moment in the Ultimate Universe.

• Character spotlight: Reed Richards (now working as Doom) and Tony Stark/Iron Lad take center stage—their alliance tests the boundaries of hero and villain.

• Universe-wide stakes: The Immortus Engine and its ability to manipulate timelines elevate the conflict from rescue missions to war across reality.

• World-building: The Ultimate Universe continues its transformation—what comes next isn’t just new heroes, it’s new rules of existence.

• Creators: Written by Deniz Camp; art by Phil Noto; cover art by Dike Ruan.

Target Audience

• Fans of the Ultimate Universe who want the architecture of reality challenged and re-imagined.

• Readers who love superhero teams with evolving identities, shifting alliances, and high-concept stakes.

• Collectors: A key issue (#17) in this relaunch series with major narrative import and variant cover potential—definitely one to secure early.

Summary

The Ultimates #17 is more than a battle—it’s a pivot point. With reality warping, allegiances fracturing, and a new “Fantastic Four” emerging under doom-shrouded terms, this issue demands attention. For fans and collectors alike, it hits the sweet spot of significance, style, and speculation.

👉 Add The Ultimates #17 to your collection today by clicking here: Affiliate Link

2. Absolute Wonder Woman #13 – The Myth Rises, Shadows Hunt

Diana of Themyscira follows a trail of supernatural attacks across the globe—each one pointing deeper into her past and the Amazon legacy she thought she abandoned. This issue sets the stage for revelations that hit closer than she expects.

About the Comic

In Absolute Wonder Woman #13, Diana travels with Barbara in Gateway City and beyond, investigating a sequence of violent mystical events. With Etta Candy at her side, she uncovers a mystery tied to her forgotten Amazon lineage—one that’s personal, powerful, and dangerous.

A Deep Dive

• Key issue alert: This issue launches the next chapter of the series, offering new mysteries about the Amazons and what Diana truly is.

• Character spotlight: Diana must lean on allies and confront what she’s kept hidden—her history and destiny collide in unexpected ways.

• Mythic stakes: The supernatural attacks aren’t random—they trace back to divine power and secret heritage, turning the global hunt into something deeply personal.

• Visual tone: With global locales and mythic horror swirling together, expect art that blends horror, myth, and epic heroism.

• Creators: Written by Kelly Thompson; art by Matías Bergara; cover art by Hayden Sherman with colors by Jordie Bellaire.

Target Audience

• Fans of Wonder Woman who appreciate mythic storytelling, hidden legacies, and supernatural stakes.

• Readers who enjoy emotional and mystical arcs where the hero’s past and identity are central to the conflict.

• Collectors: A key issue in a strong run—#13 in the Absolute Wonder Woman series, with a major direction-shift, variant covers, and a creative team with growing acclaim.

Summary

Absolute Wonder Woman #13 thrusts Diana into a global hunt for truth, her legacy looming larger than ever. With mythic menace, personal stakes, and striking art, this issue is essential for readers following her journey—and a smart pickup for collectors tracking the series’ system-shifting moments.

👉 Add Absolute Wonder Woman #13 to your collection today by clicking here: Affiliate Link

1. Ultimate Spider-Man #22 – The Last Will and Testement of...

A secret document sets a countdown in motion, and when the ink dries, the web may tighter around everyone Peter Parker cares about. Expect disappearances, exposes, and a Parker legacy under threat.

About the Comic

In Ultimate Spider-Man #22, the ramifications of Peter’s identity and legacy reach new levels. Secrets from his past, present, and future collide as one final testament forces Spider-Man into an unexpected confrontation—where what’s at stake isn’t just a city, but what he stands for.

A Deep Dive

• Key issue alert: This is a turning point issue in the new Ultimate run—issue #22 brings serious narrative weight to Spider-Man’s ongoing arc.

• Character spotlight: Peter Parker is under pressure like never before—when secrets surface, his roles as Peter, Spider-Man, husband and father all come into question.

• Legacy and stakes: The mysterious “last will” alluded to in the subtitle promises revelations about legacies—both inherited and chosen—and how far Peter will go to protect them.

• Universe implications: As part of the new Ultimate Universe imprint, this issue ties into broader world-building and may reshape how Spider-Man operates in this reality.

• Creators: Written by Jonathan Hickman; art by Marco Checchetto; cover art by Marco Checchetto with cover colors by Matt Wilson.

Target Audience

• Fans of Spider-Man who follow his evolution into a mature hero facing legacy threats and hidden history.

• Readers who enjoy high-stakes storytelling where identity, family, and heroism intersect.

• Collectors: An issue with major narrative turning points in a flagship Spider-Man series, backed by a top-tier creative team and strong setup for future issues—well worth adding early.

Summary

Ultimate Spider-Man #22 raises the bar: Peter Parker faces his past while the Ultimate Universe reshapes the future. With secrets unveiled, legacy challenged, and stakes expanded beyond street-level villainy, this issue is essential reading—and a smart acquisition for your collection.

👉 Add Ultimate Spider-Man #22 to your collection today: Affiliate Link

Conclusion

This week’s releases reflect the ever-evolving landscape of comic books. Whether you are a seasoned collector or new to the genre, there is certainly something for everyone. We hope this countdown helps you discover your next favorite read!

You can buy these from MyComicShop.com via our link below. Just click on the most recent release date once you get to their site.

https://www.mycomicshop.com/newreleases?q=newreleases&AffID=1729325P01